Mitochondrial genetic diversity, selection and recombination in a canine transmissible cancer
Canine transmissible venereal tumour (CTVT) is a clonally transmissible cancer that originated approximately 11,000 years ago and affects dogs worldwide.Despite the clonal origin of the CTVT nuclear genome, CTVT mitochondrial genomes (mtDNAs) have been acquired by periodic capture from transient hosts.We sequenced 449 complete mtDNAs from a global